Canan Şule Ünsal Karkıner, M.D.

Family Name, First Name: Unsal Karkiner Canan Sule 

Birth date and place:
1971, İzmir 

  Division of Pediatric Allergy, Dept of Pediatrics, MD, 


1988-1995 MD, Hacettepe University, School of Medicine, Ankara

1995-2000 Resident in Department of Pediatrics Dokuz Eylül University School of Medicine

2000-2003 Pediatric Allergy fellowship at Dokuz Eylül University, School of Medicine

Interested in:
Asthma, allergic rhinitis, food allergies and atopic dermatitis

Articles Published in international refereed journals

A-1. Soylu A, Kavukçu S, Turgut CS, Türkmen M, Sarioğlu S. Immune complex type crescentic glomerulonephritis and ANCA-positivity in a nine-year-old girl. Turk J Pediatr. 44(2):172-5 (2002).

A-2. Tezcan D, Uzuner N, Turgut CS, Karaman O,Köse S. Retrospective evaluation of epidermal skin prick tests in patients living in Aegean region. Allergol et Immunopathol, 31(4), 226-30 (2003).

A-3. Karaman O, Sunneli L, Uzuner N,Islekel H, Turgut CS, Köse S,Tezcan D, Coker C, Erbayraktar Z. Evaluation of montelukast in 8 to 14 year old children with mild persistent asthma and compared with inhaled corticosteroids. Allergol et Immunopathol, 32(1), 21-7 (2004).

A-4. Karaman O, Turgut CS, Uzuner N, Olmez D, Babayigit A, Kose S, Tezcan D. The determination of asthma, rhinitis, eczema and atopy prevalence in 9-11 year-old children in the city of Izmir. Allergy & Asthma Proceedings, 27(4), 319-24 (2006)

A-5. Kose S, Karaman O, Islekel H, Uzuner N, Babayigit A, Olmez D, Altun Z, Turgut CS, Tezcan D. Circulating adhesion molecules in sera of asthmatic children before and after steroid therapy. Allergy Asthma Proc, 28(2), 199-203 (2006).

A-6. Asilsoy  S, Babayigit A, Olmez D, Uzuner N, Karaman O, Oren O, Turgut CS, Tezcan D. Helicobacter Pylori Infection and Gastroesophageal Reflux in Asthmatic Children.  J Trop Pediatr, 54(2), 129-32 (2008).

A-7. Bağ O, Can D, Karaarslan U, Günay I, Turgut CS, Nacaroglu HT. Tle long-term outcomes of persistent childhood allergic asthma: A cross-sectional study from western Anatolia: Childhood persistent  asthma in western Anatolia. Allergol Immunopathol (Madr) 2012 Nov 5. Pii:S0301-0546(12)00209-1.doi:10.1016/j.aller.2012.05.008. (Epub ahead of print)

A-8. Nacaroglu HT, Celegen M, Ozek G, Umac O, Unsal Karkiner CS, Tosun Yıldırım H, Can D. Acute generalized exanthenatous pustulosis induced by ceftriaxon use. Postep Derm Alergol 2014;XXXI, 4:269-271. DOI:10.5114/pdia.2014.40938.

A-9. Nacaroglu HT, Celegen M, Ünsal Karkiner CŞ, Günay I, Diniz G, Can D. Eosinophilic cellulitis (Wells’ syndrome) caused by a temporary henna tattoo. Postepy Dermatol Alergol. Oct 2014; 31(5): 322–324. Published online Oct 22, 2014. doi:  10.5114/pdia.2014.40951

A-10. Kamalı H, Can D, Gunay I, Nacaroglu HT, Unsal Karkıner CS, Gunay T, Ozdemir A, Ayanoglu M. Prevelance of asthma among children in an industrial town. The Turkish Journal of Pediatrics 2014;56:493-499.

A-11. Nacaroglu HT, Unsal Karkıner CS, Gunay I, Bahceci S, Ayanoglu D, Dogan D, Can D. Patient compliance in subcutaneous immunotherapy. Medycyna Paliatywna 2014;6 (4):1-5.

A-12. Eren E, Arslanoglu S, Bahceci Erdem S, Nacaroglu T, Karkıner CŞ, Can D, Onal K. Chicken or the egg: the dilemma of allergic rhinitis versus adenoid hypertrophy* Rhinology 53:154-159, 2015. Doi:10.4193/Rhino14.013. 

A-13. Nacaroglu HT, Can D, Unsal Karkıner CS, Yaman Y, Alper H, Tosun Yıldırım H, Bishop PW. Neonatal systemic juvenile xanthogranuloma born to a cross-cousin marriage. Dermatologica Sinica (2015),

A-14. Bahceci Erdem S, Nacaroglu HT, Ünsal Karkıner CŞ, Özçelik G, Moğulkoç N, Alper H, Can D. Hypersensitivity pneumonia in a schoolchild admitted to the hospital’s asthma clinic. The Turkish Journal of Pediatrics 2015; 57: 529-532.

A-15. Bahceci Erdem S, Nacaroglu HT, Ünsal Karkiner CŞ, Günay İ, Can D. Side effects of leukotriene receptor antagonists in asthmatic children. Iran J Pediatr. 2015 October;25(5):e3313. DOI:10.5812/ijp.3313.

A-16. Nacaroglu HT, Can D, Unsal Karkıner CS, Yaman Y, Alper H, Tosun Yıldırım H, Bishop PW. Baby with neonatal systemic juvenile xanthogranuloma born within a cross-cousin marriage. Dermatologoca Sinica, volume33, Issue4, December 2015, pages231-233.

A-17. Bahçeci Erdem S, Nacaroglu HT, Bag O, Unsal Karkıner CS, Korkmaz HA, Can D. DRESS syndrome associated with type 2 diabetes in a child. Cent Eur J Immunol 2015; 40(4):493-496. DOI:10.5114/ceji.2015.54606.

A-18. Karaman S, Can D, Bahçeci Erdem S, Nacaroğlu HT, Karkıner CŞ, Günay I. Is there any parameter helpful for predicting a suitable candidate for mite immunotherapy? Iran J Allergy Asthma Immunol, April 2016:15(2):105-111.

A-19. Bahceci Erdem S, Nacaroglu HT, Karaman S, Unsal Karkıner CS, Gunay I, Dogan D, Asilsoy S, Altınoz S, Can D. Risk of systemic allergic resction to allergen immunotherapy in a pediatric allergy clinic in Turkey. International Journal of Pediatric Otorhinolaryngology 84(2016)55-60.

A-20. Nacaroglu HT, Bahceci Erdem S, Sümer O, Karaman S, Unsal Karkıner CS, Asilsoy S, Gunay I, Can D. Local and systemic reactions to subkutaneous allergen immunotherapy: ten years’ experience in a pediatric clinic. Annals of Allergy, Asthma & Immunology, volume116, Issue4, April 2016, pages 349-353. doi:10.1016/j.anai.2016.01.015

A-21. Erdem SB, Karaman S, Nacaroglu HT, Unsal Karkıner CS, Yazıcı S, Can D. Seizures as a rare but serious adverse effect of leukotriene receptor. Ann Allergy Asthma Immunol. 2016 Jul;117(1):99-101. doi: 10.1016/j.anai.2016.05.001. 

A-22. Bahçeci S, Karaman S, Nacaroğlu HT, Yazıcı S, Girit S, Ünsal-Karkıner Ş, Can. D. Changing epidemiology of non-cystic fibrosis bronchiectasis. Turk J Pediatr. 2016;58(1):19-26. 

A-23. Bahceci Erdem S, Nacaroglu HT, Isgüder R, Unsal Karkiner CS, Alper H, Can D. Pulmonary complications of chemical pneumonía: a case report. Arch Argent Pediatr. 2016 Aug 1;114(4):e245-8. doi: 10.5546/aap.2016.e245. English, Spanish.

A-24. Nacaroglu HT, Isguder R, Bahceci SE, Ceylan G, Korkmaz HA, Karaman S, Karkıner CS, Can D. Can mean platelet volume be used as a biomarker for asthma? Postepy Dermatol Alergol. 2016 Jun;33(3):182-7. doi: 10.5114/pdia.2015.52737.

A-25. Karaman S, Bahçeci SE, Nacaroğlu HT, Karkıner CŞ, Can D. Is Oral Provocation Test Safe for Preschool Children? Asian Pac J Allergy Immunol. 2016 Aug 16. doi: 10.12932/AP0762.   

A-26. (editöre mektup) Nacaroglu HT, İsgüder R, Bent S, Erdem Bahceci S, Ceylan G, Korkmaz HA, Karaman S, Unsal Karkiner CS, Can D. (2016). Can neutrophil/lymphocyte ratio be a novel biomarker of inflammation in children with asthma?. European Journal of Inflammation, 14(2), 109-112.

A-27. Erdem SB, Nacaroglu HT, Karaman S, Erdur CB, Karkıner CU, Can D. Tolerance development in food protein-induced allergic proctocolitis: Single centre experience. Allergol Immunopathol (Madr). 2017 May - Jun;45(3):212-219. doi: 10.1016/j.aller.2016.10.005. Epub 2017 Feb 1. PubMed PMID: 28159385.

A-28. H.T. Nacaroglu, S.B. Erdem, S. Karaman, D. Dogan, C.S. U.Karkiner, E. T. Kanık, D. Can. Diagnostic values for egg white specific IgE levels with the skin prick test in Turkish children with egg white allergyAllergologia et Immunopathologia, Volume 45, Issue 5, September–October 2017, Pages 445 - 451

A-29. Nacaroğlu HT, Bahçeci Erdem S, Gülez N, Ünsal Karkıner CŞ, Devrim İ, Genel F, Köker MY, Can D. Tuberculosis masked by immunodeficiency: a review of two cases diagnosed with chronic granulomatous disease. Tuberk Toraks. 2017 Mar;65(1):56-59. PubMed PMID: 28621249.

A-30. Bahceci Erdem S, Nacaroglu HT, Isgüder R, Unsal Karkiner CS, Alper H, Can D. Pulmonary complications of chemical pneumonia: a case report. Arch Argent Pediatr. 2017 Aug 1;115(4):e245-e248. doi: 10.5546/aap.2017.eng.e245. English, Spanish. PubMed PMID: 28731666.

A-31. Karaman SBahçeci SENacaroğlu HTKarkıner CŞCan D. Is Oral Food Challenge (OFC) test safe for preschool children? Asian Pac J Allergy Immunol. 2017 Dec;35(4):220-223. doi: 10.12932/AP0762.

A-32. Nacaroglu HT, Can D, Gunay I, Unsal Karkıner CS, Gunay T, Cimrin D, Nalcabasmaz T. Does raising awareness in families reduce environmental tobacco smoke exposure in wheezy children? Adv Dermatol Allergol 2017; XXXIV (4): 350–356 DOI:

A-33. Nacaroglu HTBahceci Erdem SDurgun EKaraman SBaris Erdur CUnsal Karkıner CSCan D. Markers of inflammation and tolerance development in allergic proctocolitis. Arch Argent Pediatr. 2018 Feb 1;116(1):e1-e7. doi: 10.5546/aap.2018.eng.e1.