T.C. MİNİSTRY OF HEALTH İZMİR PROVINCIAL HEALTH DIRECTORATE S.B.Ü. DR.BEHÇET UZ CHİLDREN'S EDUCATİON AND RESEARCH HOSPİTAL
T.C. MİNİSTRY OF HEALTH İZMİR PROVINCIAL HEALTH DIRECTORATE S.B.Ü. DR.BEHÇET UZ CHİLDREN'S EDUCATİON AND RESEARCH HOSPİTAL

Facebook Twitter Google Plus Linkedin

Melis Köse, M.D.

Updated: 14/03/2019

Date of birth : 1982 –  Turkey

Marital Status: Married, One children

Education

1998 – 2004 Uludağ  University Medical School   Bursa  - Turkey   2000  MD, 5th graduate degree

 

Postgraduate training:

  1. İzmir  Behçet Uz Children Hospital / Registrar in Department of Pediatrics/ November 2005- September 2010

Thesis: Evaluation of p dyspersion as a finding of autonomic dysfunction  in children with vasovagal syncope

  1. Ege University Medical School Hospital  /  Registrar in Department of Pediatrics /Metabolism Unit / November   2011 (Prof.Dr.Mahmut Çoker)
  2. Behçet Uz Children Training and Research Hospital, Department of Pediatrics /Metabolism Unit , February, 2015
  3. PhD Program on Genetics, Ege University Medical Faculty, August 2017 (Prof.Dr.Ferda Özkınay)
  • Ongoing Projects:
    • Autophagy in Activator Protein Deficiencies  (Izmir Institute of Technology)

 

Presantation in international congress

Poster Presantations:

 

1.     Melis Köse, Mehtap Kağnıcı, Ebru Canda,Sema Kalkan Uçar, Mahmut Çoker.Is it possible to evaluate dopaminergic activity in gaucher disease by measuring  prolactin concentration? SSIEM 2012 Conference , Birmingham ,UK

2.     Melis Köse, Ebru Canda , Hüseyin Onay, Serkan Kurtgöz, Mehtap Kağnıcı, Sema Kalkan Uçar, Sara Habif , Oya Bayındır, Ferda Özkınay, Mahmut Çoker. A new case wıth bıotınıdase defıcıency and alcaptonurıa , SSIEM 2012 Conference , Birmingham ,UK

3.     Ebru Canda, Melis Köse, Mehtap Kağnıcı, Sema Kalkan Uçar, Mahmut Çoker .Follow-up of mucopolysaccharidosis Type IVa Patients:Ege University Experience SSIEM 2012 Conference , Birmingham ,UK

4.     Mehtap Kağnıcı , Ebru Canda , Melis Köse , Zülal Ülger , Sema Kalkan Uçar , Ertürk Levent , Ruhi Özyürek , Mahmut Çoker . Evaluation of cardiac manifestations in muchopolysaccharidoses , SSIEM 2012 Conference , Birmingham ,UK

5.     Mehtap Kağnıcı, Emin Karaca, Ebru Canda, Melis Köse, Sema Kalkan Uçar, Gül Serdaroğlu,Ferda Özkınay, Sarenur Gökben, Mahmut Çoker .  Metachromatic leukodystrophy ın assocıatıon wıth hirschsprung dısease, a case report , SSIEM 2012 Conference , Birmingham ,UK

6.     Ebru Canda, Mehtap Kağnıcı, Melis Köse, Sema Kalkan Uçar, Mahmut Çoker .Follow-up of gaucher patıents: Ege Unıversıty experıence , SSIEM 2012 Conference , Birmingham ,UK

7.     Eser Yıldırım Sözmen,   Sündüs Ekinci , Mehtap Kağnıcı, Ebru Canda, Melis Köse, Sema Kalkan Uçar, Mahmut Çoker.Lysosomal Enzyme assay  datas of Ege University Metabolism Labaratory. III.Turkish National Lysosomal Sorage Disorders Congress 2012 ,Cyprus

8.     Melis Köse, Ebru Canda, Mehtap Kağnıcı, Yasemin Atik Altınok, Sema Kalkan Uçar, Mahmut Çoker . Fatty liver and dyslipidemia  as an important clues  for diagnosis of cholesterol ester storage disease , IX. Turkish National Gastroenterology and Hepatology Congress 2012 , Antalya , Turkey

9.     Melis Köse , Mehtap Kağnıcı , Ebru Canda, Sema Kalkan Uçar, Yasemin Atik Altınok, Funda Özgenç, Sema Aydoğdu, Raşit Vural Yağcı, Mahmut Çoker . Follow-up aminoacidopathies as metabolic liver disease : Ege Unıversıty experıence , IX. Turkish National Gastroenterology and Hepatology Congress 2012 , Antalya , Turkey

10.  Ebru Canda , Melis Köse , Mehtap Kağnıcı , Sema Kalkan Uçar , Funda Özgenç , Sema Aydoğdu , Raşit Vural Yağcı , Mahmut Çoker. Congenital organel diseases of liver : Ege Unıversıty experıence , IX. Turkish National Gastroenterology and Hepatology Congress 2012 , Antalya , Turkey

11.  Mehtap Kağnıcı  , Ebru Canda , Melis Köse , Sema Kalkan Uçar , Funda Özgenç , Sema Aydoğdu , Raşit Vural Yağcı , Mahmut Çoker .Congenital carbonhydrate metabolism disorders of liver: Ege Unıversıty experıence , IX. Turkish National Gastroenterology and Hepatology Congress 2012, Antalya , Turkey

12.  Melis Köse, Ebru Canda, Mehtap Kağnıcı, Yasemin Atik Altınok, Sema Kalkan Uçar, Ertürk Levent, Mahmut Çoker: Dispersion of the P wave and QT segment as a test for cardiac autonomic function in Phenylketonuria. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

13.  Melis Köse, Ebru Canda, Mehtap Kağnıcı, Sema Kalkan Uçar, Kimiyochi Ichida, Mahmut Çoker: A novel mutation in a Turkish case with molybdenum cofactor deficiency. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

14.  Melis Köse, Ebru Canda, Mehtap Kağnıcı, Rana İşgüder, Sema Kalkan Uçar, Bähr L, Britschgi C, Sass JO, Çoker M: Different clinical presentations in siblings with mitochondrial acetoacetyl-CoA thiolase deficiency. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

15.  Melis Köse, Mehtap Kağnıcı, Ebru Canda, Sema Kalkan Uçar, Gülden Diniz Ünlü, Robert Taylor, Garry Brown, Mahmut Çoker: A case report of COX deficient leigh syndrome due to SURF1 gene mutation. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

16.  Melis Köse, Mehtap Kağnıcı, Ebru Canda, Can Balkan, Mahmut Çoker: Platelet function and coagulation abnormalities in Gaucher disease patients. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

17.  Melis Köse, Mehtap Kağnıcı, Ebru Canda, Nihal Karadaş, Volkan Okur, Asude Alpman, Sema Kalkan Uçar, Hüseyin Onay, Eser Yıldırım Sözmen, Deniz Karapınar, Ferda Özkınay, Mahmut Çoker: Coexistence of Gaucher disease and severe congenital neutropenia in Turkish patient. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

18.  Melis Köse, Ebru Canda, Mehtap Kağnıcı, Sema Kalkan Uçar, Ertürk Levent, Mahmut Çoker: Follow-up our pediatric patients with lipoprotein (a) axcess. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.

19.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Serkan Kurtgöz, Ömer Kitiş, Sema Kalkan Uçar, Mahmut Çoker: Female child with X linked adrenoleukodystrophy. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

20.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Sema Kalkan Uçar, Mahmut Çoker: Adult MPS VI patient diagnosed with cardiac manifestations. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

21.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Ayça Aykut, Sema Kalkan Uçar, Hüseyin Onay , Ferda Özkınay, Mahmut Çoker: Follow-up of Niemann Pick type B patients: Ege University experience. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

22.  Mehtap Kağnıcı, Melis Köse, Ebru Canda, Miray Karakoyun, SemaKalkan Uçar , Funda Özgenç , Mahmut Çoker : Hepatocellular carcinoma in hereditary tyrosinemia, a case report. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

23.  Ebru Canda, Mehtap Kağnıcı, Melis Köse, Betül Sözeri, Asude Alpman, Sema Kalkan Uçar, Hüseyin Onay, Ferda Özkınay, Mahmut Çoker: Niemann Pick type B patient with arthritis: should we think Niemann Pick type B disease for the differential diagnosis of rheumatologic disorders. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

24.  Ebru Canda, Mehtap Kağnıcı, Melis Köse, Sema Kalkan Uçar , Mahmut Çoker: Follow-up of Niemann Pick type C patients: Ege University experience. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.

25.  Mehtap Kağnıcı, Yasemin Atik Altınok, Melis Köse, Ebru Canda, Sema Kalkan Uçar , Sara Habif, Mahmut Çoker : BH4 responsiveness: Ege University experience. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona

26.  Mehtap Kağnıcı, Yasemin Altınok, Ebru Canda, Melis Köse, Emin Karaca, Sema Kalkan Uçar, Hüseyin Onay, Ferda Özkınay, Mahmut Çoker: Follow-up infants with hypertriglyceridemia. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona.  

27.  Mehtap Kağnıcı, Yasemin Altınok, Ebru Canda, Melis Köse, Emin Karaca, Sema Kalkan Uçar, Hüseyin Onay, Ferda Özkınay, Mahmut Çoker Pompe disease in association with hydrocephalus, a case report. ICIEM 2013, 12th International Congress of Inborn Errors of Metabolism, 3 – 6 September 2013, Barcelona

28.  Ayça Aykut, Hüseyin Onay, Melis Kose, Ebru Erbas Canda, Emin Karaca, Mahmut Coker, Ferda Ozkinay: Two novel mutations in acid a-glucosidase gene in two patients with Pompe disease. American Society of Human Genetics 63rd Annual Meeting, October 22–26, 2013 Boston

29.  Melis Köse, Mehtap Kağnıcı, Ebru Canda, Yasemin Altınok, Sema Kalkan Uçar, Sara Habif, Mahmut Çoker. A patient with HMGCoA Lyase deficiency. 10th MEMG ( Middle East Metabolic Group ) Meeting, 5 – 7 December 2013, İstanbul

30.  Melis Köse, Ebru Canda, Mehtap Kağnıcı, Yasemin Altınok, Sema Kalkan Uçar, Mahmut Çoker. A patient with congenital lactic acidosis, what could it be? 10th MEMG ( Middle East Metabolic Group ) Meeting, 5 – 7 December 2013, İstanbul

31.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Yasemin Altınok, Serap Nur Ergör, Özgün Uygur , Demet Terek, Deniz Gönülal, Özge Altun Köroğlu, Şebnem Çalkavur , Sema Kalkan Uçar , Mehmet Yalaz,  Sara Habif , Nilgün Kültürsay, Johannes Haberle,  Mahmut Çoker. Two cases with citrullinemia type 1 diagnosed during neonatal period. 10th MEMG ( Middle East Metabolic Group ) Meeting, 5 – 7 December 2013, İstanbul

32.  Ebru Canda, Mehtap Kağnıcı, Melis Köse, Yasemin Altınok, Ayça Aykut, Sema Kalkan Uçar, Hüseyin Onay, Sara Habif, Ferda Özkınay, Mahmut Çoker. The case of lysinuric protein intolerance with a novel mutation. 10th MEMG ( Middle East Metabolic Group ) Meeting, 5 – 7 December 2013, İstanbul

33.  Melis Köse, Ebru Canda, Ayça Aykut, Mehtap Kağnıcı, Hüseyin Onay, Sema Kalkan Uçar Afig Berdeli,  Ferda Özkınay, Mahmut Çoker. Coexıstence Of Nıemann Pıck Type B And Familial Mediterranean Fever In A Turkısh Patient. ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

34.  Melis Köse, Mehtap Kağnıcı, Ebru Canda, Yasemin Altınok, Serdar Ceylaner, Sema Kalkan Uçar, Mahmut Çoker HmgCoA Lyase Deficiency: One Disease Three Pictures. ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

35.  Mehtap Kağnıcı, Melis Köse, Ebru Canda, Ayça Aykut, Emin Karaca, Sema Kalkan Uçar, Zulal Ülger, Ertürk Levent, Hüseyin Onay, Eser Sözman Yıldırım, Ruhi Özyürek, Fatih Ezgü, Ferda Özkınay, Mahmut Çoker. A Turkish patient with Gaucher disease having infantile portal hypertension: Homozygosity for the double D409H + H255Q allele. ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

36.  Ebru Canda, Melis Köse,Mehtap Kağnıcı, Sara Habif, Sema Kalkan Uçar, Mahmut Çoker.Two Cases With Oxoprolinuria: 5-Oxoprolinase  Deficiency? ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

37.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Sema Kalkan Uçar, Mahmut Çoker. Fucosidosis Case Report:  Rare Cause of Developmental Delay.ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

38.  Mehtap Kağnıcı, Ebru Canda, Melis Köse, Sema Kalkan Uçar, Eser Y. Sözmen, Sara Habif, Mahmut Çoker. The Effect Of Tetrahydrobıopterın On Oxidative Stress In Hyperphenylalaninemıa ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

39.  Ebru Canda, Mehtap Kağnıcı, Melis Köse,Yasemin Altınok, Ayça Aykut, Asude Durmaz, Sema Kalkan Uçar, Hüseyin Onay, Sara Habif, Ferda Özkınay, Mahmut Çoker Lysinuric Protein Intolerance: Keep in mind on hyperammonemia.  ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

40.  Mehtap Kağnıcı, Ebru Canda, Melis Köse, Ayça Aykut, Emin Karaca, Asude Durmaz,Sema Kalkan Uçar, Zülal Ülger, Ertürk Levent, Hüseyin Onay, Eser Y. Sözmen, Ruhi Özyürek, Ferda Özkınay, Mahmut Çoker. A Review Of Our Patients With Pompe Disease: Four Identified Novel Mutations. ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

41.  Mehtap Kağnıcı, Ebru Canda, Melis Köse, Sema Kalkan Uçar, Afig Berdeli, Mahmut Çoker. Infantile Nephropathic Cystinosis With Severe Gastrointestinal Manifestations: A Case Report. ICIEM 2014, 13th International Congress of Inborn Errors of Metabolism, 2–5 September 2014, Barcelona

42.  Melis Köse, Ebru Canda, Miray Karakoyun, Mehtap Kağnıcı, Havva Yazıcı, Yasemin Atik Altınok, Sema Kalkan Uçar, Funda Özgenç, Sema Aydoğdu, Hüseyin Onay, Sara Habif, Mahmut Çoker. The Struggle of Two Sisters With Metylmalonıc Aciduria: Before And After Liver Transplantation. ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

43.  Melis Köse, Ebru Canda, Yasemin Atik Altınok, Sema Kalkan Uçar, Sara Habif, Mahmut Çoker. Nutrition and Growth In Branched-Chain Aminoacidopathy Patients. ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

44.  Melis Köse, Ebru Canda, Mehtap Kağnıcı, Şule Gökçe Bozkurt, Ertürk Levent, Sema Kalkan Uçar, Serdar Ceylaner, Ruhi Özyürek,  Mahmut Çoker.A Case with Kerns Sayre Syndrome and Definition of an Atypical Mutation. ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

45.  Melis Köse, Ebru Canda, Mehtap Kağnıcı , Sema Kalkan Uçar, Mahmut Çoker.  OurPatients with Congenital Disorders of Glycosylation.ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

46.  Sema Kalkan Uçar, Melis Köse, Yasemin Atik Altınok, Ebru Canda, Mehtap Kağnıcı, Muhterem Duyu, Caner Kabasakal, Sara Habif, Mahmut Çoker. A Patient With MSUD: Attack Management With Sodium Phenylbutirate And Hemodialysis.ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

47.  Sema Kalkan Uçar, Melis Köse, Ebru Canda, Mehtap Kağnıcı, Serdar Ceylaner, Mahmut Çoker. A Case With SURF-1 Mutation  And Hypertrophic Olivary Nuclear Degeneration.ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

48.  Mahmut Çoker, Melis Köse, Ebru Canda, Mehtap Kağnıcı, Desiree Smith, Marisa Mendes, Sema Kalkan Uçar, Gaija Salomons5,10-Methylenetetrahydrofolate Reductase Deficiency with  Different Pictures.  ICIEM 2015, 14th International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

49.  Mahmut Çoker, Melis Köse, Ebru Canda, Mehtap Kağnıcı, Yasemin Atik Altınok Sema Kalkan Uçar, Sara Habif, Hüseyin Onay. Branched-Chaın Amınoacıdopathy:

             Our Experience in Ege University Faculty of Medicine. ICIEM 2015, 14t International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

50.  Ebru Canda, Melis Köse, Ayfer Arduç Akçay, Sema Kalkan Uçar, Bülent Karapınar, Mahmut Çoker. Two Patients with Tyrosinemia Type 1 and Neurogenic Crisis. ICIEM 2015, 14t International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

51.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Havva Yazıcı, Caner Kabasakal, Sara Habif, Sema Kalkan Uçar, Mahmut Çoker. SCOT Deficiency: Effectiveness of  Periton Dialysis During Attack. ICIEM 2015, 14t International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

52.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Miray Karakoyun, İsmail Kurt, Serap Aksoylar, Sema Kalkan Uçar, Yeşim Aydınok, Savaş Kansoy, Mahmut Çoker. Accute Intermittant Porphiria and Congenital Eritropoetic Porphiria Cases: Our Experience in Ege University Faculty of Medicine. ICIEM 2015, 14t International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

53.  Sema Kalkan Uçar, Ebru Canda, Melis Köse, Mehtap Kağnıcı, Serap Aksoylar, Ömer kitiş, Ayşe Tosun, Savaş Kansoy, Mahmut Çoker. Hematopoetic Stem Cell Transplantation Cases With X linked  Adrenoleukodystrophy and Metachromatic Leukodystrophy. ICIEM 2015, 14t International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

54.  Mahmut Çoker, Ebru Canda, Mehtap Kağnıcı, Melis Köse, Ayşe Tosun, Sema Kalkan Uçar. Our Patients With Neuronal Ceroid Lipofuscinoses. ICIEM 2015, 14t International Congress of Inborn Errors of Metabolism, 1–4 September 2015, Lyon

55.  Melis Köse, Mehtap Kağnıcı, Ebru Canda, Cenk Eraslan, Gülden Diniz, Gülçin Akıncı, Aycan Ünalp, Ünsal Yılmaz, Serdar Ceylaner, Sema Kalkan Uçar, Rob Taylor, Mahmut Çoker. Clinical, molecular, radiological investigations in patients withSURF1mutations and muscle biopsy findings. ICIEM 2016, 15th International Congress of Inborn Errors of Metabolism, 6-9 September 2016, Rome

56.  Melis Köse, Mehtap Kağnıcı, Cahit Barış Erdur, Gülin Erdemir, Miray Karakoyun, Emel Berksoy, Özlem Bağ, Serdar Ceylaner, Ferah Genel. Clinical and Molecular Investigations in Five Turkish Patients withCitrinDeficiencyand Identification of a Novel Mutation onSLC25A13. ICIEM 2016, 15th International Congress of Inborn Errors of Metabolism, 6-9 September 2016, Rome

57.  Ebru Canda, Melis Köse, Mehtap Kağnıcı, Meral Dondurmacı, Sema Kalkan Uçar, Eser Sözmen, Ertürk Levent, Mahmut Çoker. Evaluation of Cardiac and Vascular Involvement in Patients with Mucopolysaccharidosis. ICIEM 2017, 16th International Congress of Inborn Errors of Metabolism, 5-8 September 2016, Rio de Janerio

Oral Presantations:

 

1.     Melis Köse, Mehtap Kağnıcı, Ebru Canda,Sema Kalkan Uçar, Mahmut Çoker.Is it possible to evaluate dopaminergic activity in gaucher disease by measuring  prolactin concentration?III.Turkish National Lysosomal Sorage Disorders Congress 2012 ,Cyprus

2.     Melis Köse, Ebru Canda, Mehtap Kağnıcı, Yasemin Atik Altınok, Sema Kalkan Uçar, Sara Habif, Hüseyin Oany, Mahmut Çoker. Branched Chain Aminoacidopathies: Ege University Experience. XIII. Turkish National Metabolism Congress 2015, Adana, Turkey

3.     Melis Köse, Mehtap Kağnıcı, Ebru Canda, Cenk Eraslan, Gülden Diniz, Gülçin Akıncı, Aycan Ünalp, Ünsal Yılmaz, Serdar Ceylaner, Sema Kalkan Uçar, Rob Taylor, Mahmut Çoker. Clinical, molecular, radiological investigations in patients withSURF1mutations and muscle biopsy findings. XV. Turkish National Metabolism Congress 2017, Antalya, Turkey

4.     Melis Köse, Gülçin Akıncı, Aycan Ünalp, Cenk Eraslan, Eser Sözmen Yıldırım, Mahmut Çoker. A new case of  Saposin A Deficiency with a novel mutation. XV. Turkish National Metabolism Congress 2017, Antalya, Turkey

5.     Melis Demir Köse, Hüseyin Onay, Tuba Hilkay Karapinar, Yeşim Oymak, Eser Sözmen Yildirim, Ferda Özkınay. Hematological and Molecular Genetic Results of Gaucher Disease Patients and definition of a novel mutation. III. Ege University Hematology& Genetic Symposium 2018, Izmir, Turkey

6.     Melis Köse, Seçil Akyıldız Demir, Gülçin Akıncı, Cenk Eraslan, Ünsal Yılmaz, Serdar Ceylaner, Eser Sözmen Yıldırım, Volkan Seyrantepe. Second case of  Saposin A Deficiency and Altered Autophagy. VI. Lysosomal Disorders Congress with International Participation 2018,Antalya,Turkey

Courses:

1.   European focus course on Congenital Disorders of Glycosylation – CDG, 26-28 June 2013, Nijmegen, The Netherlands

2.   European focus Course on Neurotransmitter Deficiencies , 8-10 November 2015, Venice, Italy

Publications:

 

1.     Melis Köse , Özlem Bağ, Barış Güven, Timur Meşe, Aysel Öztürk, Vedide Tavlı. P-wave dispersion: an indicator of cardiac autonomic dysfunction in children with neurocardiogenic syncope.Pediatr Cardiol. 2014 April;35(4):596-600. doi: 10.1007

2.     Ayça Aykut A, Hüseyin Onay H,Melis Köse, Ebru Canda, Emin Karaca, Mahmut Coker, Ferda Ozkınay.Two novel mutations in acid α-glucosidase gene in two patients with Pompe disease. J Pediatr Endocrinol Metab. 2014 Nov;27(11-12):1265-7. doi: 10.1515

3.     Ayşe Nil Kavasoglu, Hüseyin Onay, Melis Kose, Asude Durmaz, Ferda Ozkınay. A case diagnosed with biotinidase deficiency in newborn screening test. Apr 2014 · Turkiye Klinikleri Pediatri

  1. Sema Kalkan Uçar, Ebru Canda, Melis Köse, Mehtap Kağınıcı, Özge Altun Köroğlu, Şebnem Çalkavur, Sara Habif, Mahmut Çoker.  Presentation and management of classical urea cycle disorders: lessons from our experience.  Behcet Uz Cocuk Hast Derg. 2016; 6(2): 89-96 | DOI:10.5222/buchd.2016.089  
  2. Sema Kalkan  Uçar, Burcu Özbaran, Yasemin  Atik Altinok, Melis Köse, Ebru Canda, Mehtap Kagnici, Mahmut Çoker. One Year Experience of Pheburane® (Sodium Phenylbutyrate) Treatment in a Patient with Argininosuccinate Lyase Deficiency. JIMD Rep. 2015 Feb 10. [Epub ahead of print]
  3. Melis Demir Köse, Ebru Canda, Mehtap Kağnıcı, Yasemin Atik Altınok, Sema Kalkan Uçar, Sara Habif, Hüseyin Onay, Mahmut Coker. Branched chain organic organic acidurias: Experience of Ege University Medical Faculty. J Pediatr Res 2016; 3: 76-81
  4. Melis Demir Köse, Ebru Canda, Mehtap Kağnıcı, Rana İşgüder,  Aycan Ünalp, Sema Kalkan Uçar, Luzy Bahr, Corinne Britschgi, Jörn Oliver Sass, Mahmut Coker. Two Siblings with Beta-Ketothiolase Deficiency: One Genetic Defect Two Different Pictures. J Pediatr Res 2016; 3: 113-116
  5. Ebru Canda, Melis Demir Köse, Mehtap Kağnıcı, Sema Kalkan Uçar, Eser Sözmen Yıldırım, Mahmut Coker. Patients with Gaucher type 1: Switching from imiglucerase to miglustat therapy. Blood Cells Mol Dis. 2018 Feb;68:180-184
  6. Melis Köse, Ebru Canda, Mehtap Kağnıcı, Sema Kalkan Uçar, Mahmut Coker.A Patient with MSUD: Acute Management with Sodium Phenylacetate/Sodium Benzoate and Sodium Phenylbutyrate. Case Rep Pediatr. 2017;2017:1045031.
  7. Melis Köse, Mahmut Çoker.Primary Neurotransmitter Disorders. Journal of Tepecik Training and Research Hospital 2017; 27(3):169-178
  8. Kayikcioglu M, Tokgozoglu L, Yilmaz M, Kaynar L, Aktan M, Durmuş RB, Gokce C, Temizhan A, Ozcebe OI, Akyol TK, Okutan H, Sag S, Gul OO, Salcioglu Z, Yenercag M, Altunkeser BB, Kuku I, Yasar HY, Kurtoglu E, Kose MD, Demircioglu S, Pekkolay Z, Ilhan O. A nation-wide survey of patients with homozygous familial hypercholesterolemia phenotype undergoing LDL-apheresis in Turkey (A-HIT 1 registry).Atherosclerosis. 2018 Mar;270:42-48. doi:10.1016/j.atherosclerosis.2018.01.034.  Epub 2018 Jan 31